Email this article SPECIFIC USE OF SCREENING IMMUNOCHROMATOGRAPHIC TESTS FOR THE PRIMARY DETECTION OF FACTS OF PSYCHOACTIVE SUBSTANCE USE IN URINE AND SALIVA
- Authors: Agudina V.A.1
-
Affiliations:
- NEARMEDIC PLUS LLC
- Issue: Vol 5, No 2 (2019)
- Pages: 83-94
- Section: ORIGINAL ARTICLE
- URL: https://seamed.bmoc-spb.ru/jour/article/view/298
- DOI: https://doi.org/10.22328/2413-5747-2019-5-2-83-94
- ID: 298
Cite item
Full Text
Abstract
The use of narcotic substances is a serious social problem, a threat to the health of an individual and to the security of the country as a whole. The use of narcotic substances affects the safety of the overall productivity of labor, which, ultimately, creates a rather large burden on the economy of the country as a whole. In the framework of federal programs for the prevention of drug addiction, the practice of testing for the use of narcotic drugs at work and study places is being increasingly used. And here the question naturally arises of the significant cost, laboriousness and time-consuming test systems for the use of narcotic substances produced by Russian companies. All this, of course, complicates the process of introducing a testing procedure. In this situation, the importance of developing, improving and introducing new methods for the detection of narcotic substances and their metabolites in human biological fluids increases. The article provides a general overview of world experience in using immunochromatographic tests for identifying psychoactive substances as a screening test, with particular attention being paid to analyzing the specifics of using screening immunochromatographic tests for the initial identification of psychoactive substances in urine and saliva from the standpoint of the contextual feasibility of their applicability in a number of specific cases related to the specifics of the professional activities of the test. Along with this, the author, on the basis of the available statistical information and original research materials, provides an analysis of the Russian market of test systems for the detection of psychoactive substances in saliva and examines the feasibility of expanding its capabilities through wider use of screening psychoactive substances for saliva.
About the authors
V. A. Agudina
NEARMEDIC PLUS LLC
Author for correspondence.
Email: fake@neicon.ru
Moscow Russian Federation
References
- EU action plan on drugs 2017–2020 // Official Journal of the European Union. 2017. Vol. IV. P. 215–221.
- European drug report // European Monitoring Centre for Drugs and Drug Addiction. 2018. 96 p.
- Report on roadside drug testing and equipment and related matters // Medical Bureau of Road Safety. 2012. June. P. 44–47.
- Игумнов С.А., Станько Э.П., Гелда А.П. Карта аддиктивного поведения потребителей инъекционных наркотиков с различным ВИЧ-статусом для динамической оценки эффективности лечения: учебно-методическое пособие. Минск, 2012. 79 c.
- Verstraete A.G. Detection times of drugs of abuse in blood, urine and oral fluid // Ther. Drug Monit. 2004. Vol. 26. P. 200–205.
- Wu A.H.B., Bristol B., Sexton K., Cassella-McLane G., Holtman V., Hill D.W. Adulteration of urine by «Urine Luck» // Clin. Chem. 1999. Vol. 45 (7). P. 1051–1057.
- Tsai L.C., ElSohly M.A., Tsai S.F., Murphy T.P., Twarowska B., Salamone S.J. Investigation of nitrite adulteration on the immunoassay and GC-MS analysis of cannabinoids in urine specimens // J. Anal. Toxicol. 2000. Vol. 24. P. 708–714.
- Tsai S.-C.J., EISohly M.A., Dubrovsky T., Twarowska B., Towt J., Salamone S.J. Determination of five abused drugs in nitrite-adulterated urine by immunoassay and gas chromatography-mass spectrometry // J. Anal. Toxicol. 1998. Vol. 22. P. 474–480.
- Urry F.M., Komaromy-Hiller G., Staley B. Nitrite adulteration of workplace urine drug-testing specimens. Sources and associated concentrations of nitrite in urine and distinction between natural sources and adulteration // J. Anal. Toxicol. 1998. Vol. 22. P. 89–95.
- George S., Braithwaite R.A. The effect of glutaraldehyde adulteration of urine specimens on syva EMIT II drugs-ofabuse assays // J. Anal. Toxicol. 1996. Vol. 20 (3). P. 195–201. 11. Cody J.T., Valtier S., Kuhlman J. Analysis of morphine and codeine in samples adulterated with stealth // J. Anal. Toxicol. 2001. Vol. 25. Р. 572–575.
Supplementary files
