SARCOIDOSIS IN MILITARY PERSONNEL: BASES OF DIAGNOSTICS, TREATMENT AND FOLLOW-UP

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Abstract

Sarcoidosis is an urgent problem for the military medical service of various law enforcement agencies. In recent years, there has been an increase in the incidence of sarcoidosis among young people undergoing military service and the creation of a unified algorithm of medical care for this contingent is important. The publication presents the epidemiology of the disease, known risk factors, and triggers for the development of sarcoidosis in military sailors. The most important factors associated with a high risk of sarcoidosis are: high dustiness of the air, diesel and rocket fuel vapors, and various types of radiation. In military personnel, the second stage of sarcoidosis is most common. The recurrence rate of the disease is 20%, and the factors associated with the recurrent course of sarcoidosis in military personnel are — the age of more than 35 years; the presence of clinical manifestations of sarcoidosis (cough, weakness, shortness of breath); forced lung capacity <85%; a history of systemic glucocorticosteroids. The article presents the recommended algorithm and methods for examining patients with sarcoidosis. It is noted that the main point is the mandatory morphological verification of the process in the military. Special attention is paid to the treatment of sarcoidosis in the publication. It is noted that, given the high frequency of remissions, treatment is not indicated for stage I, as well as for asymptomatic patients with stages II and III of sarcoidosis, provided that only mild disorders of the ventilation and diffusion function of the lungs are present. All patients with sarcoidosis are subject to active medical supervision.

About the authors

A. A. Zaitsev

Central research Institute of epidemiology of Rospotrebnadzor

Email: a-zaicev@yandex.ru
ORCID iD: 0000-0002-0934-7313

Зайцев Андрей Алексеевич — доктор медицинских наук, профессор, ведущий научный сотрудник

111123, Москва, Новогиреевская ул., д. 3а

 

Russian Federation

A. A. Wiesel

Kazan State Medical University

Email: lordara@inbox.ru
ORCID iD: 0000-0001-5028-5276

Визель Александр Андреевич — доктор медицинских наук, профессор, заведующий кафедрой фтизиопульмонологии

420012, г. Казань, ул. Бутлерова, д. 49

Russian Federation

D. N. Antipushina

Central research Institute of epidemiology of Rospotrebnadzor

Author for correspondence.
Email: antipushina@mail.ru
ORCID iD: 0000-0001-9267-4931

Антипушина Диана Николаевна — кандидат медицинских наук, старший научный сотрудник

111123, Москва, Новогиреевская ул., д. 3а

SPIN-код: 7040-9401

Russian Federation

References

  1. Ungprasert P., Ryu J., Matteson E. Clinical Manifestations, Diagnosis, and Treatment of Sarcoidosis // Mayo Clin. Proc. Innov. Qual. Outcomes. 2019. Vol. 3, No. 3. P. 358–375. doi: 10.1016/j.mayocpiqo.2019.04.006.
  2. Саркоидоз: монография / под ред. А.А. Визеля (Серия монографий Российского респираторного общества; гл. ред. серии А.Г. Чучалин). М.: Издательский холдинг «Атмосфера», 2010. 416 с. [Sarcoidosis: monograph / еd. A.A. Wiesel (Series of monographs of the Russian Respiratory Society; еd. series by A.G. Chuchalin). Moscow: Atmosphere Publishing Holding, 2010. 416 p. (In Russ.)].
  3. Визель А.А., Визель И.Ю., Амиров Н.Б. Эпидемиология саркоидоза в Российской Федерации // Вестник современной клинической медицины. 2017. Т. 10, № 5. С. 66–73. [Wiesel A.A., Wiesel I.Yu., Amirov N.B. Epidemiology of sarcoidosis in the Russian Federation. Bulletin of modern clinical medicine, 2017, Vol. 10, No. 5, рр. 66–73 (In Russ.)]. doi: 10.20969/VSKM.2017.10(5).66–73.
  4. Зайцев А.А., Антипушина Д.Н., Сивокозов И.В., Чернов С.А. Диагностика и лечение пациентов с саркоидозом в многопрофильном военном стационаре // Военно-медицинский журнал. 2012. Т. 333, № 9. С. 35–40. [Zaitsev A.A., Antipushina D.N., Sivokozov I.V., Chernov S.A. Diagnosis and treatment of patients with sarcoidosis in a multidisciplinary military hospital. Military Medical Journal, 2012, Vol. 333, No. 9, рр. 35–40 (In Russ.)].
  5. Крюков Е.В., Антипушина Д.Н., Зайцев А.А. Саркоидоз — актуальная проблема различных силовых ведомств // Вестник Российской военно-медицинской академии. 2016. № 4 (56). С. 224–227. [Kryukov E.V., Antipushina D.N., Zaitsev A.A. Sarcoidosis is an urgent problem of various law enforcement agencies. Bulletin of the Russian Military Medical Academy, 2016, No. 4 (56), рр. 224–227 (In Russ.)].
  6. Gorham E., Garland C., Garland F. еt al. Trends and occupational associations in incidence of hospitalized pulmonary sarcoidosis and other lung diseases in Navy personnel: a 27-year historical prospective study, 1975–2001. // Chest. 2004. Vol. 126. P. 1431–1438. doi: 10.1378/chest.126.5.1431.
  7. Hosoda Y., Sasagawa S., Yasuda N. Epidemiology of sarcoidosis: new frontiers to explore // Cur. Opinion in Pulmonary Medicine. 2002. Vol. 8 (5). P. 424–428.
  8. McDonough C., Gray G. Risk factors for sarcoidosis hospitalization among US Navy and Marine Corps Personnel, 1981 to 1995 // Military Med. 2000. Vol. 165. P. 630–632.
  9. Зайцев А.А. Эпидемиология заболеваний органов дыхания у военнослужащих и направления по совершенствованию пульмонологической помощи // Военно-медицинский журнал. 2018. № 11. C. 4–9. [Zaitsev A.A. Epidemiology of respiratory diseases in military personnel and directions for improving pulmonological care. Military Medical Journal, 2018, No. 11, рр. 4–9 (In Russ.)].
  10. Hunninghake G.W., Costabel U., Ando M. American Thoracic Society / European Respiratory Society / World Association of Sarcoidosis and other Granulomatous Disorders ATS/ERS/WASOG statement on sarcoidosis // Sarcoidosis Vasc. Diffuse Lung Dis. 1999. Vol. 16 (2). Р. 149–173.
  11. Овчинников Ю.В., Крюков Е.В., Зайцев А.А., Антипушина Д.Н. Клинико-диагностические и организационные аспекты оказания помощи больным саркоидозом органов дыхания в Вооруженных силах // Военно-медицинский журнал. 2014. Т. 335, № 11. C. 35–43. [Ovchinnikov Yu.V., Kryukov E.V., Zaitsev A.A., Antipushina D.N. Clinical, diagnostic and organizational aspects of assisting patients with respiratory sarcoidosis in the Armed Forces. Military Medical Journal, 2014, Vol. 335, No. 11, рр. 35–43 (In Russ.)].
  12. Зайцев А.А., Крюков Е.В., Антипушина Д.Н. Саркоидоз: критерии и инструменты прогноза рецидивирующего течения // Практическая пульмонология. 2015. № 2. C. 28–31. [Zaitsev A.A., Kryukov E.V., Antipushina D.N. Sarcoidosis: criteria and tools for predicting a recurrent course. Practical pulmonology, 2015, No. 2, рр. 28–31 (In Russ.)].
  13. Антипушина Д.Н., Зайцев А.А. Саркоидоз органов дыхания у военнослужащих // Вестник современной клинической медицины. 2015. Т. 8, № 3. C. 7–11. [Antipushina D.N., Zaitsev A.A. Respiratory sarcoidosis in military personnel. Bulletin of modern clinical medicine, 2015, Vol. 8, No. 3, рр. 7–11 (In Russ.)].
  14. Савушкина О.И., Антипушина Д.Н., Зайцев А.А. Роль комплексного исследования респираторной функции в выявлении вентиляционно-диффузионных нарушений у больных саркоидозом органов дыхания в многопрофильном военном стационаре // Пульмонология. 2015. Т. 25, № 1. C. 82–85. [Savushkina O.I., Antipushina D.N., Zaitsev A.A. The role of a comprehensive study of respiratory function in identifying ventilation-diffusion disorders in patients with respiratory sarcoidosis in a multidisciplinary military hospital. Pulmonology, 2015, Vol. 25, No. 1, рр. 82–85 (In Russ.)].
  15. Крюков Е.В., Зайцев А.А., Чернецов В.А., Антипушина Д.Н. Клинические и прогностические аспекты саркоидоза органов дыхания у военнослужащих // Военно-медицинский журнал. 2015. Т. 336, № 10. C. 26–29. [Kryukov E.V., Zaitsev A.A., Chernetsov V.A., Antipushina D.N. Clinical and prognostic aspects of respiratory sarcoidosis in military personnel. Military Medical Journal, 2015, Vol. 336, No. 10, рр. 26–29 (In Russ.)].
  16. Зайцев А.А., Овчинников Ю.В., Кондратьева Т.В. Биологические маркеры воспаления при внебольничной пневмонии // Consilium Medicum. 2014. Т. 16, № 11. C. 36–41. [Zaitsev A.A., Ovchinnikov Yu.V., Kondratyeva T.V. Biological markers of inflammation in community-acquired pneumonia. Consilium Medicum, 2014, Vol. 16, No. 11, рр. 36–41 (In Russ.)].
  17. Синопальников А.И., Зайцев А.А Медленно разрешающаяся/неразрешающаяся внебольничная пневмония // РМЖ. 2009. Т. 17, № 5. C. 361–367. [Sinopalnikov A.I., Zaitsev A.A. Slow-resolving/non-resolving community-acquired pneumonia. Russian medical journal, 2009, Vol. 17, No. 5, рр. 361–367 (In Russ.)].
  18. Coker R.K. Guidelines for the use of corticosteroids in the treatment of pulmonary sarcoidosis // Drugs. 2007. Vol. 67 (8). Р. 1139–1147.
  19. Sarcoidosis / еd. by M. Drent, U. Costabel. Monography ERS, 2005. 32 р.
  20. Paramothayan S., Jones P.W. Corticosteroid therapy in pulmonary sarcoidosis: a systematic review // JAMA. 2002. Vol. 287 (10). Р. 1301–1307.
  21. Park M.K., Fontana Jr., Babaali H., Gilbert-McClain L.I., Stylianou M., Joo J., Moss J., Manganiello V. Steroid-sparing effects of pentoxifylline in pulmonary sarcoidosis // Sarcoidosis. Vasc. Diffuse Lung. Dis. 2009. Vol. 26, No. 2. Р. 121–131.

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