CURRENT CONCEPTS OF THE PATHOGENESIS, PREVENTION AND TREATMENT OF THE MOTION DISEASE (SEASICKNESS)

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Abstract

Motion  disease (naupathia, seasickness) is quite prevalent among otherwise healthy people  and  is manifested as travel sickness associated with  nausea. It  is a complex physiological response to certain motor stimuli caused by  ship  rocking, aircraft  swinging or  zero  gravity.  The  motor stimuli may  be  both  real (ship  rocking) and  virtual (watching a 3D movie).  During the  last  decade, numerous studies addressed different stimuli that can  cause naupathia, and  numerous hypotheses have been  put  forward to explain it (sensory conflict,  postural instability etc.) from  the  point of view  of neural plasticity. However, no consensus concerning the  origin  of the  specific  clinical  pattern of naupathia (nausea, vomiting, drowsiness, dysphoria etc.) has emerged by now. Several drugs and  behavioral recommendations have been  suggested for  prevention and  treatment of naupathia. Further studies of this  condition using such  techniques as videonystagmography and  computer-assisted posturegraphy, as well  as genetic analysis, are  warranted. 

About the authors

I. V. Litvinenko

S. M. Kirov Military Medical Academy

Author for correspondence.
Email: litvinenkoiv@rambler.ru
St. Petersburg Russian Federation

I. N. Samartsev

S. M. Kirov Military Medical Academy

Email: alpinaigor@mail.ru
St. Petersburg Russian Federation

S. A. Zhivolupov

S. M. Kirov Military Medical Academy

Email: peroslava@yandex.ru
St. Petersburg Russian Federation

M. V. Morozova

S. M. Kirov Military Medical Academy

Email: mariia.v.morozova@gmail.com
St. Petersburg Russian Federation

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