Abstract
We analyzed the age criteria, time of admission, comorbidities and structure of chronic obliterating atherosclerosis therapy of lower limb arteries. It was found that the degree of severity of chronic ischemia of the lower limb arteries atherosclerotic lesions does not correlate with the age factor, however, is closely associated with the time of admission of patients to the hospital. Early treatment for medical patients with III and IV degree of chronic lower limb ischemia is associated with the presence of this category of persons expressed pain in the legs and feet and trophic complications, pathogenetic link which is circulatory, and then cellular hypoxia, leading to cell death and tissue up to the development of focal necrosis. In the structure of concomitant chronic lower limb ischemia pathologies dominate diseases of the cardiovascular system (coronary heart disease and hypertension) in 100% of patients, nervous system diseases (encephalopathy) in 76,9% of patients, indicating that systematic, generalized atherosclerosis obliterans, which is characterized by involvement in the pathological process is not only lower limb arteries, and distant arterial pools of organs and systems. It has been shown that the combined application of traditional preparations of basic therapy, intravenous infusions of ozonated saline reopoliglyukina trentalom with sulodexide and shown to be highly effective in chronic critical limb ischemia therapy. Patients with chronic obliterating atherosclerosis of the arteries of the lower extremities is necessary to conduct a life-long therapy with regular cardiovascular hospitalizations not less than 2 times a year for routine preventive treatment.