Abstract
Geographical and climatic conditions of the Crimean peninsula, mammals of a particular ecosystem together with pathogens of the infection and a complex of their ectoparasites, contribute to the preservation of natural foci of tularemia and other natural focal infectious diseases on its territory. Epizootic activity of natural foci of tularemia has a welldefined periodicity and seasonality. Currently, natural foci of tularemia of the steppe type in the flat Crimea and forest type on the territory of the mountain-forest Crimea function. Three types of enzootic tularemia were identified. The epidemiological analysis of people with tularemia in the Crimea showed that its dynamics, level and distribution of cases in the administrative regions are determined primarily by the activity and duration of epizootics in natural foci located in the territories where tularemia is diagnosed. Prevention of diseases of people with tularemia in the Crimea, requires constant monitoring of the activity of natural foci of these infections, the timely detection of rodent epizootics, the study of their ectoparasites and their results, and the implementation of preventive measures.