А case of heparin-induced thrombocytopenia in a patient with a novel coronaviral infection, features of diagnosis and treatment in a naval hospital conditions
- Authors: Shapovalov I.D.1, Makarchenko V.E.1, Kartina O.Y.1, Belousova T.L.1
-
Affiliations:
- 1477th Naval Hospital
- Issue: Vol 7, No 3 (2021)
- Pages: 71-77
- Section: ORIGINAL ARTICLE. NAVAL MEDICINE
- URL: https://seamed.bmoc-spb.ru/jour/article/view/460
- DOI: https://doi.org/10.22328/2413-5747-2021-7-3-71-77
- ID: 460
Cite item
Full Text
Abstract
The heparin-induced thrombocytopenia is a severe, potentially life-threatening complication of heparinotherpapia associated with thrombosis, develops as a result of antibody-mediated platelet activation. In the context of the SARS CoV-2 pandemic, the frequency of use of heparin in clinical practice has significantly increased, as a result of which the doctors have become more likely to face this complication. The article presents a review of the literature, describes the pathogenesis, modern algorithms for diagnosis and treatment, demonstrates a clinical case of heparin-induced thrombocytopenia in a patient with the SARS CoV-2, and discusses the features of diagnosis and treatment of this complication in a naval hospital.
About the authors
I. D. Shapovalov
1477 th Naval Hospital
Author for correspondence.
Email: ilshapovalov@yandex.ru
Ilya D. Shapovalov.
Vladivostok.
Russian FederationV. E. Makarchenko
1477 th Naval Hospital
Email: fake@neicon.ru
Vladislav E. Makarchenko.
Vladivostok.
Russian FederationO. Yu. Kartina
1477 th Naval Hospital
Email: fake@neicon.ru
Oksana Yu. Kartina.
Vladivostok.
Russian FederationT. L. Belousova
1477 th Naval Hospital
Email: fake@neicon.ru
Tatyana L. Belousova.
Vladivostok.
Russian FederationReferences
- Дударенко С.В., Ежова О.А. Гепарининдуцированная тромбоцитопения // Неотложная кардиология и кардиоваскулярные риски. 2018. Т. 2, № 1. С. 252-257.
- Семиголовский Н.Ю., Вавилова Т.В., Кащенко В.А., Семиголовский С.Н., Сапегин А.А. Гепарининдуцированная тромбоцитопения у пациентов с венозными тромбоэмболическими осложнениями — клинические наблюдения и обзор литературы // Медицинский совет. 2018. № 5. С. 110-116.
- Васильев С.А., Горгидзе Л.А., Моисеева Т.Н., Аль-Ради Л.С., Зозуля Н.И., Соколова М.А., Мазуров А.В. Гепарининдуцированная тромбоцитопения (обзор) // Атеротромбоз. 2019. № 1. С. 99-114.
- Дуткевич И.Г., Сухомлина Е.Н., Селиванов Е.А. Основы клинической гемостазиологии. СПб.: ООО ИПК Коста, 2010. 144 с.
- Самсонова Н.Н., Климович Л.Г., Рогальская Е.А. Патогенез послеоперационных коагулопатий // Клиническая физиология кровообращения. 2014. № 4. С. 17-24.
- Марченко И.А., Шиян А.В., Андреева А.С. Современные методы лабораторной диагностики гепарин-индуцированной тромбоцитопении // Медицинский совет. 2017. № 12. С. 189-195.
- Временные методические рекомендации «Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 9 (26.10.2020)» (утв. Минздравом России).
- Greinacher A., Warkentin T.E. Recognition, treatment, and prevention of heparin-induced thrombocytopenia: review and update // Thromb. Res. 2006. Vol. 118, No. 2. Р. 165-176.
- Watson H., Davidson S., Keeling D. Guidelines on the diagnosis and management of heparin-induced thrombocytopenia: second edition // Br. J. Haematol. 2012. Vol. 159, No. 5. Р. 528-540.
- Warkentin T.E. Heparin-induced thrombocytopenia: pathogenesis and management // Br. J. Haematol. 2003. Vol. 121, No. 4. Р. 535-555.
- Linkins L.A., Dans A.L., Moores L.K., Bona R., Davidson B.L., Schulman S. et al. Treatment and prevention of heparin-induced thrombocytopenia. Antithrombotic Therapy and Prevention of Thrombosis. American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. 9th ed. // Chest. 2012. Vol. 141. Р. 495-530.
- Seigerman M., Cavallaro P., Itagaki S., Chung I., Chikwe J. Incidence and outcomes of heparin-induced thrombocytopenia in patients undergoing cardiac surgery in North America: An analysis of the nation — wide inpatient sample // J. Cardiothorac. Vasc. Anesth. 2014. Vol. 28. Р. 98-102.
- Cucer A., Gowthami M.A., Beng H.C., Douglas B.C. ASH 2018 guidelines for management of venous thromboembolism: heparin-induced thrombocytopenia // Blood Adv. 2018. Vol. 2, No. 22. Р. 3360-3392.
- Lingamaneni P., Gonakoti S., Moturi K., Vohra I., Zia M. Heparin-Induced Thrombocytopenia in COVID-19 // J. Investig. Med. High Impact Case Rep. 2020. Jan-Dec. Vol. 8. 2324709620944091. doi: 10.1177/2324709620944091.
- Sartori M., Cosmi B. Heparin-induced thrombocytopenia and COVID-19 // Hematol. Rep. 2021. Mar 12. Vol. 13, No. 1. Р. 8857. doi: 10.4081/hr.2021.8857. eCollection 2021 Mar 5.